GLP-1 Side Effects Explained by Doctors: What Patients Should Know

Introduction

GLP-1 medications such as Ozempic, Wegovy, Mounjaro, and Zepbound are transforming how patients manage type 2 diabetes and obesity. While these medications can help with weight loss and blood sugar control, many patients worry about possible side effects.

At Medical Wellness Doc in Chula Vista, Dr. Nisha Kuruvadi provides expert, evidence-based guidance on GLP-1 medications. This article breaks down the most common side effects, how serious they are, and what patients should expect.

What Are GLP-1 Medications?

GLP-1 receptor agonists are a class of drugs that:

• Help the body release insulin after meals

• Slow digestion, which reduces appetite

• Improve blood sugar levels

• Support significant weight loss

Examples include Ozempic (semaglutide), Wegovy (semaglutide for weight loss), Mounjaro (tirzepatide), and Zepbound (tirzepatide for weight loss).

Common GLP-1 Side Effects (Usually Mild)

Most side effects occur early in treatment and improve over time as the body adjusts:

• Nausea → Most common, often reduced by eating smaller meals.

• Vomiting → May occur in some patients during dose escalation.

• Diarrhea or constipation → Digestive system slowdown is common.

• Bloating or gas → Linked to slowed stomach emptying.

• Decreased appetite → Often viewed positively as it supports weight loss.

👉 At Medical Wellness Doc, Dr. Nisha helps patients titrate doses carefully to minimize these symptoms.

Less Common but Possible Side Effects

While less frequent, some patients may experience:

• Fatigue

• Dizziness

• Injection site reactions (redness, itching, swelling)

• Mild headaches

These usually resolve on their own or with minor adjustments.

Rare but Serious GLP-1 Side Effects

Though uncommon, patients should be aware of potential risks:

• Pancreatitis (inflammation of the pancreas) → Severe abdominal pain should be reported immediately.

• Gallbladder issues → Including gallstones in some cases.

• Kidney function changes → Especially in those with preexisting kidney disease.

• Thyroid tumors (seen in animal studies, not confirmed in humans).

👉 Patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia (MEN) syndrome are usually not candidates.

How Doctors Manage GLP-1 Side Effects

Dr. Nisha helps patients minimize risks by:

• Gradual dose escalation → Prevents overwhelming the body.

• Dietary adjustments → Small, balanced meals reduce nausea.

• Regular monitoring → Blood tests and checkups to ensure safety.

• Personalized treatment → Not every patient needs the same medication or dose.

This careful approach ensures GLP-1 medications are both safe and effective.

Should You Stop GLP-1 If You Experience Side Effects?

Not necessarily. Many side effects are temporary and manageable. Patients should always consult their doctor before stopping treatment. In most cases, adjustments can be made without discontinuing the medication.

Why Choose Medical Wellness Doc for GLP-1 Treatment?

• Triple board-certified expertise → Internal Medicine, Obesity Medicine, Lifestyle Medicine.

• Personalized plans → Medication combined with plant-based nutrition and lifestyle support.

• Telehealth options → Ongoing virtual care for California patients.

• Safe prescribing practices → Focused on long-term wellness, not quick fixes.

Call to Action (CTA)

GLP-1 medications are powerful tools for weight loss and diabetes management—but they require expert oversight.

📅 Schedule a consultation with Dr. Nisha at Medical Wellness Doc in Chula Vista to learn if GLP-1 therapy is right for you.

Final Thoughts

Every medication comes with side effects, but with the right guidance, GLP-1 therapies are safe, effective, and life-changing for many patients.

By working with an experienced physician like Dr. Nisha Kuruvadi, you’ll not only understand the risks but also have a trusted partner to guide you every step of the way.